Histone Acetylation and Chromatin Assembly: A Single Escort, Multiple Dances?
نویسندگان
چکیده
منابع مشابه
Histone Acetylation and Chromatin Assembly: A Single Escort, Multiple Dances?
acetylation is carried out by HAT A activities. Until reThe compaction of eukaryotic DNA into chromatin dicently, little was known about the regulation of these rectly affects transmission of genetic material to daughHATs because none had been isolatedand cloned. Howter cells as well as the establishment of specific patever, the landmark cloning of the catalytic subunit of a terns of gene expre...
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In eukaryotes, the interaction of DNA with proteins and supramolecular complexes involved in gene expression is controlled by the dynamic organization of chromatin inasmuch as it defines the DNA accessibility. Here, the nuclear distribution of microinjected fluorescein-labeled dextrans of 42 kDa to 2.5 MDa molecular mass was used to characterize the chromatin accessibility in dependence on hist...
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histone acetylation, one of the first and best studied histone post-translational modifications (ptms), as well as the factors involved in its deposition (writers), binding (readers) and removal (erasers), have been shown to act at the heart of regulatory circuits controlling essential cellular functions. the identification of a variety of competing histone lysine-modifying acyl groups includin...
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In this issue, two papers implicate histone H3 lysine 56 acetylation in histone deposition in chromatin. Li et al. (2008) show that acetylation of H3K56 promotes S phase chromatin assembly that is mediated by the histone chaperones CAF-1 and Rtt106. Chen et al. (2008) establish that the acetylation mark promotes chromatin reassembly following DNA double-strand break repair.
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ژورنال
عنوان ژورنال: Cell
سال: 1996
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(00)81316-1